Dates of birth and death unknown. He was one of the first Kabuki performers in Edo. He was the master of Saruwaka Kanzaburô from 1622.
In 1624, he took the name of Mikuni Hikosaku I and worked as a tôdori at the Saruwakaza,
which was managed by his disciple Saruwaka Kanzaburô.
In 1636, both Mikuni Hikosaku I and Saruwaka Kanzaburô were chastised by the authorities for the use of lavish costumes on stage.
Hikosaku performed, along with Murayama Matasaburô I, at the Edo Castle in the 9th lunar month of 1650.
Hikosaku performed, along with Saruwaka Kanzaburô, at the Edo Castle in the 2th lunar month of 1651.
Wakashû Kabuki ("Boy Kabuki") was forbidden in the 7th lunar month of 1652 by the Shogunal authorities. Hikosaku worked as a aizamoto with Ichimura Uzaemon III to manage the Murayamaza.
Yarô Kabuki (Adult Kabuki) was authorized by the Shogunal authorities in the 3rd lunar month of 1653.
Hikosaku worked as a aizamoto at the Ichimuraza in 1661 and 1662.
No record afterwards.
He was the father of Mikuni Hikosaku II.