The play "Honchô Nijûshikô" was originally written for the puppet theater (Bunraku) and staged for the first time in the 1st lunar month of 1766 in Ôsaka at the Takemotoza. It was adapted to Kabuki a few months later and was produced by both Nakamura Utaemon I and Mimasu Daigorô I in Ôsaka at the Naka no Shibai [casting].

"Dôsan Saigo" ("The End of Dôsan" in English) is the common nickname for the last act of "Honchô Nijûshikô". It is no more part of the current Kabuki repertoire

While trying to go by stealth to the room of Nagao Kenshin late at night, Sekibê is caught by Nagao Kagekatsu and Takeda Katsuyori (disguised as the gardener Minosaku), who have come back from their respective trips to Shiojiri, and Yamamoto Kansuke, an eminent strategist, who is on Shingen's payroll. Sekibê is in fact the villain nyûdô Saitô Dôsan, who assassinated the Shôgun three years ago. The two daimyô Nagao Kenshin and Takeda Shingen have been pretending to be antagonistic to each other in order to outmaneuver Dôsan, who has been plotting to bring about the downfall of both Kenshin and Shingen and eventually to overthrow the Shôgunate government.

Though surrounded by his enemies, Dôsan defiantly declares that he has assassinated Lady Taoyame with the same rifle as the one used by him for the assassination of the Shôgun. Actually, however, the victim proves to be Nureginu. Kenshin, who had anticipated Dôsan's attack on Lady Taoyame, secretly disguised Nureginu as Lady Taoyame, thereby causing Dôsan to unknowingly kill his own daughter. Kenshin shoots Dôsan to death with an arrow, bringing the rebel's plot to a disastrous end.

A picture for the last scene of "Honchô Nijûshikô" from the ezukushi banzuke for the staging in the 1st lunar month of 1766 in Ôsaka at the Takemotoza of the puppet play "Honchô Nijûshikô"